# AI Biologist - Structural Biology at LatchBio

- Company: LatchBio
- Status: Open
- Workplace: Remote
- Location: San Francisco or Remote · Remote
- Level: Mid-level
- Discipline: AI & ML
- Employment: Full-time
- Posted: 2026-10-26
- Skills: AI, Structural Biology
- Apply: https://jobs.ashbyhq.com/latchbio/ba71439b-6f26-48b5-af5c-5449289274e0

## Description

AI Biologist - Structural Biology

Latch builds rigorous scientific benchmarks (benchmarks.bio http://benchmarks.bio) for AI agents across biology. We work with frontier labs and pharma to measure whether agents can handle real biological workflows: the messy, multi-layer reasoning that matters in the field.

We're seeking an AI Biologist to join our Structural Biology team, pushing what AI can achieve in interpreting macromolecular structure.




About the Role. You will be the scientific authority on ground truth, testing whether agents can reason like an expert structural biologist. AI agents today read a deposited model as fact. They miss that a ligand sits in empty density, that the two chains in a crystal file are a packing contact rather than the biological dimer, that a confident AlphaFold prediction shows the wrong conformational state, or that a stretch of chain is built out of register. Separating what the data actually support from what the model asserts is the core of the job. Knowing where the evidence ends, and when a structure cannot support a claim, is part of the work.

The role is intentionally broad, spanning molecular systems, experimental and computational methods, and questions from structure determination to interaction analysis, molecular dynamics, and functional interpretation. You will work with software engineers and scientists to build benchmark tasks and datasets across viral and bacterial proteins, toxins, RNA elements, and host–pathogen complexes. Your judgment will set the standard for agent outputs across these areas, including:



Build th

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