AI Biologist - Peptide Discovery

AI Biologist - Peptide Discovery

Latch builds rigorous scientific benchmarks (benchmarks.bio http://benchmarks.bio) for AI agents across biology. We work with frontier labs and pharma to measure whether agents can handle real biological workflows: the messy, multi-layer reasoning that matters in the field.

We’re seeking an AI Biologist to join our Peptide Discovery team, pushing what AI can achieve in therapeutic peptide discovery.

About the Role. You will be the scientific authority on ground truth, testing whether agents can reason like an expert peptide discovery scientist. AI agents today struggle to interpret raw selection, biophysical, and structural data, to separate true hits from artifacts, and to make the calls that move a peptide from target to candidate. The data often misleads: enrichment can be a propagation artifact, protection is not contact, and binding is not function. Knowing what the evidence actually supports is the work. You will work with software engineers and scientists to build the tasks and datasets behind our benchmarks. They span linear, macrocyclic, and constrained peptides against protein targets, including protein–protein interactions, from target tractability to candidate nomination. Your judgment will set the standard agent outputs are held to, including:

Build the task

• Define what expert reasoning looks like for a peptide discovery question, and write gold-standard answers with the rationale an experienced peptide scientist would defend
• Design realistic scenarios across the discovery arc: target tractability, hit generatio